Dr. Simon Rüdisser

Senior Scientist

Biomolecular NMR and scientific computing

Dr. Rüdisser earned his PhD from the University of Innsbruck, where he studied the role of hydration in RNA and DNA dynamics under the supervision of Prof. Mayer. He then moved to UC Berkeley as a postdoctoral researcher in Prof. Tinoco’s lab, focusing on RNA structure via NMR spectroscopy. In 1999, he joined Prof. Bodenhausen’s group at EPFL to develop novel methods for
studying hydrogen-bond dynamics in RNA.

Transitioning to industry in 2000, Dr. Rüdisser served as a Lab Head at Novartis in Basel, where he integrated fragment-based screening with molecular docking. During his tenure, his expertise in biomolecular NMR contributed to several successful drug discovery projects. Since 2017, he has been a member of the ETH Biomolecular NMR Platform. There, he leverages his extensive background in biomedical research and scientific computing to advance NMR methodology, structure elucidation, and the application of machine learning in drug discovery.